Skip to main content
Testing version — LOERadar is in active testing. Features and data may change.
LOERadar
LOE
Radar
Hub
News
Changes
Search
Log in
Get Started
OTEZLA XR (APREMILAST) | LOERadar
Viewing data from:
Latest
2026-07-01
2026-06-01
2026-05-01
2026-04-01
2026-03-28
2026-02-17
2026-02-10
2025-12-14
2025-02-26
2025-01-25
2024-11-08
2023-07-23
2023-06-15
2023-05-13
2023-01-26
2022-11-22
2022-10-28
2022-09-29
2022-07-09
2022-06-29
2022-04-08
2022-03-09
2021-12-28
2021-05-05
2021-03-12
2020-12-22
2020-11-12
2019-12-14
2019-09-15
OTEZLA XR
NDA
Get alerts
APREMILAST | N210745 | AMGEN INC
1 strength
5 unique patents
3 unique exclusivities
Patents
SEC Intel
Revenue
PTAB
Reexams
Litigation
Petitions
Trials
DMF
Approvals
Label
Products
Patent Timeline
5 unique patents, 2 exclusivities by expiration date
Active (5)
Today
PED (+6 mo)
Exclusivity
2026
2027
2028
2029
2030
2031
2032
2033
2034
2035
2036
2037
2038
2039
2040
2041
2042
2043
Today
7427638
Feb. 16, 2028
10092541
May. 29, 2034
11752129
May. 27, 2042
11969409
May. 27, 2042
12427136
May. 27, 2042
ODE*
Jan. 19, 2027
M-299
Jan. 19, 2027
PTAB Proceedings
No IPR/PGR/CBM challenges found at the Patent Trial and Appeal Board
Hatch-Waxman Litigation
No ANDA patent litigation cases (NOS 835) matched from PACER
Citizen Petitions
No FDA citizen petitions matched from Regulations.gov
Products (1)
#001 — 75MG
RLD
5 patents
3 exclusivities
▴
TABLET, EXTENDED RELEASE;ORAL | Approved: Aug 29, 2025
Patents (5)
Patent #
Expiration
PED
Drug Substance
Drug Product
Use Code
Delist
7427638
Feb 16, 2028
—
Yes
Yes
—
—
10092541
May 29, 2034
—
—
—
U-2659
TREATMENT OF ADULT PATIENTS WITH ORAL ULCERS ASSOCIATED WITH BEHCET'S DISEASE USING A DOSAGE TITRATION SCHEDULE
—
11752129
May 27, 2042
—
—
Yes
U-4264
TREATMENT OF ORAL ULCERS ASSOCIATED WITH BEHCET'S DISEASE BY ADMINISTERING APREMILAST WITH FOOD
—
11969409
May 27, 2042
—
—
Yes
—
—
12427136
May 27, 2042
—
—
—
U-1858
TREATMENT OF PLAQUE PSORIASIS
—
Exclusivities (3)
Code
Date
Status
M-299
Jul 20, 2026
< 1 year
ODE*
Jul 19, 2026
< 1 year
PED
Jan 19, 2027
< 1 year